User applied drug labels in anaesthesia: time for action

Evaluation of several drug combinations for intraperitoneal anaesthesia in adult male rats

The objective of this study was to evaluate several drug combinations for intraperitoneal anaesthesia in laboratory rats. Following dose determination of anaesthetics in a pilot study, 45 healthy adult male rats were randomly assigned in 9 treatment groups and received propofol (alone or in combination with xylazine, midazolam, or ketamine) or ketamine (in combination with xylazine, midazolam, ...

Physics Applied to Anaesthesia

Applied Anatomy for Anaesthesia and Intensive Care.

Dr Andy Georgiou holds first-class honours in Anatomical Science and has demonstrated anatomy at the University of Bristol. He is now a consultant in anaesthesia and intensive care medicine at the Royal United Hospital in Bath. Dr Chris Thompson holds the European Diploma in Regional Anaesthesia. He is a consultant in anaesthesia and a specialist in regional anaesthesia at North Bristol NHS Tru...

Drug cessation in complex older adults: time for action.

BACKGROUND general opinion is growing that drug cessation in complex older patients is warranted in certain situations. From a clinical viewpoint, drug cessation seems most warranted in four situations, i.e., falls, delirium, cognitive impairment and end-of-life situations. To date, little information about the effects of drug cessation in these four situations is available. OBJECTIVES to ide...

Pharmacogenetic information for patients on drug labels

Advances in pharmacogenetic research have improved our understanding of adverse drug responses and have led to the development of pharmacogenetic tests and targeted drugs. However, the extent of the communication process and provision of information to patients about pharmacogenetics is unclear. Pharmacogenetic information may be included in sections of a drug's package insert intended for pati...